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The Mouse Stroke Unit Protocol with Standardized Neurological Scoring for Translational Mouse Stroke Studies
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Simplified modified Rankin Scale questionnaire correlates with stroke severity.

Askiel Bruno1, Brian Close, Jeffrey A Switzer

  • 1Department of Neurology, Georgia Health Sciences University, GA, USA. abruno@georgiahealth.edu

Clinical Rehabilitation
|February 16, 2013
PubMed
Summary

The simplified modified Rankin Scale questionnaire (smRSq) shows good correlation with initial stroke severity, validating its use for assessing patient functional outcomes post-stroke.

Keywords:
Strokecerebral infarctionstroke outcome

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Area of Science:

  • Neurology
  • Clinical Outcomes Research
  • Health Informatics

Background:

  • Assessing functional outcome after stroke is crucial for patient management.
  • The modified Rankin Scale (mRS) is a standard tool, but its lengthy administration can be a barrier.
  • The simplified modified Rankin Scale questionnaire (smRSq) offers a potentially more efficient alternative.

Purpose of the Study:

  • To validate the simplified modified Rankin Scale questionnaire (smRSq).
  • To compare the smRSq against initial stroke severity as a predictor of functional outcome.

Main Methods:

  • Retrospective correlation analysis of 40 stroke patients treated with intravenous tissue plasminogen activator.
  • Initial stroke severity assessed using the National Institutes of Health Stroke Scale (NIHSS) via a telestroke system.
  • Functional outcomes assessed using the smRSq via telephone at least three months post-stroke.

Main Results:

  • A good correlation was found between the initial NIHSS scores and the smRSq assessments (r = 0.69, R(2) = 0.47, P < 0.001).
  • The 40 patients included in the analysis had baseline characteristics similar to the 80 disqualified patients.
  • The smRSq demonstrated good reliability in assessing functional outcomes.

Conclusions:

  • The strong correlation between smRSq and initial stroke severity supports its validity.
  • The smRSq is a reliable tool for assessing functional outcomes after stroke.
  • This validation furthers the utility of the smRSq in clinical practice and research.