Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 14, 2026

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

Sentinel node in ovarian cancer: study protocol for a phase 1 study.

Marjolein Kleppe1, Toon Van Gorp, Brigitte F M Slangen

  • 1Department of Obstetrics and Gynecology, Maastricht University Medical Centre, PO Box 5800 6202 AZ, Maastricht, The Netherlands.

Trials
|February 19, 2013
PubMed
Summary

Sentinel lymph node biopsy is a key cancer staging technique. This study assesses its feasibility in ovarian cancer patients using tracers injected into ovarian ligaments.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Differences in overall survival for invasive epithelial ovarian cancer by race and ethnicity: results from the Ovarian Cancer Association Consortium.

British journal of cancer·2026
Same author

Alterations in the MAPK pathway: promising biomarkers for MEK1/2 inhibition.

Gynecology and pelvic medicine·2026
Same author

Patients' Perception of Follow-Up Care and Personal Health Status of 677 Long-Term Survivors of Gynecological Cancer from the Study "Expression IX-Long-Term Survival with Gynecological Cancer": The International NOGGO, ENGOT and GCIG Survey.

Cancers·2026
Same author

A randomized, open-label phase II non-inferiority study of niraparib maintenance after 3 versus 6 cycles of platinum-based chemotherapy in patients with completely debulked advanced HRD-positive high-grade ovarian cancer in first-line therapy (N-PLUS/NOGGO-ov53/ENGOT-ov62).

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2026
Same author

Reconsidering the control arm in hyperthermic intra-peritoneal chemotherapy trials for epithelial ovarian cancer: are we comparing equivalent chemotherapy exposure?

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2026
Same author

Tisotumab vedotin plus carboplatin or pembrolizumab in recurrent or metastatic cervical cancer: 5-year results from the innovaTV 205/ENGOT-cx8/GOG-3024 study.

Gynecologic oncology·2026

Area of Science:

  • Oncology
  • Surgical Oncology
  • Gynecologic Oncology

Background:

  • Sentinel lymph node (SLN) surgery identifies cancer spread to the first lymph node.
  • This technique is effective across various cancer types.
  • Its application in ovarian cancer requires further investigation.

Purpose of the Study:

  • To evaluate the feasibility of SLN biopsy in ovarian cancer patients.
  • To determine if tracers injected into ovarian ligaments can identify SLNs.
  • To assess the efficacy of SLN identification in this specific patient group.

Main Methods:

  • The study included patients with suspected ovarian malignancy or endometrial cancer.
  • Blue dye and radioactive colloid were injected into the ovarian ligaments (ligamentum ovarii proprium and ligamentum infundibulo-pelvicum).

More Related Videos

An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses
10:35

An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses

Published on: November 28, 2010

Related Experiment Videos

Last Updated: May 14, 2026

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses
10:35

An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses

Published on: November 28, 2010

  • Feasibility of SLN identification, anatomical location, and false negative rates were analyzed.

    • Main Results:

    • The study aimed to calculate the percentage of patients where SLNs could be identified.
    • It also focused on the anatomical localization of identified SLNs.
    • The incidence of false negative lymph nodes was another key parameter.

    Conclusions:

    • The study's findings will determine the viability of SLN biopsy for ovarian cancer staging via ovarian ligament tracer injection.
    • Results will inform potential improvements in surgical staging for gynecologic malignancies.
    • This research contributes to the understanding of SLN mapping in ovarian cancer.