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Peroxisome formation and maintenance are dependent on the endoplasmic reticulum

Henk F Tabak1, Ineke Braakman, Adabella van der Zand

  • 1Section of Cellular Protein Chemistry, Faculty of Science, Utrecht University, NL-3584 CH Utrecht, the Netherlands.

Annual Review of Biochemistry
|February 19, 2013
PubMed

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The endoplasmic reticulum or ER makes up for more than half of the membranes in a cell and accounts for 10% of total cell volume. It is also the primary protein and lipid synthesis factory for most cell organelles, such as the Golgi apparatus, lysosomes, secretory vesicles, and the plasma membrane. Despite being the most extensive and functionally complex subcellular organelle, ER was the last to be discovered. After years of deliberation, Keith Porter and George Palade in the year 1954,...
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