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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

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Related Experiment Video

Updated: May 14, 2026

Study of Experimental Organ Donation Models for Lung Transplantation
08:56

Study of Experimental Organ Donation Models for Lung Transplantation

Published on: March 15, 2024

The Organ Donation Breakthrough Collaborative: has it made a difference?

Barry D Davis1, H James Norton, David G Jacobs

  • 1Department of Surgery, F.H. Sammy Ross Jr Trauma Center, Carolinas Medical Center, 1000 Blythe Boulevard, MEB #601, Charlotte, NC 28203, USA.

American Journal of Surgery
|February 19, 2013
PubMed
Summary
This summary is machine-generated.

The Organ Donation Breakthrough Collaborative (ODBC) showed increased organ donation consent rates at one institution but not overall. Efforts are needed to improve and sustain consent rates for all racial groups, especially minorities.

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Area of Science:

  • Transplantation Science
  • Public Health Initiatives
  • Organ Donation Research

Background:

  • The Organ Donation Breakthrough Collaborative (ODBC) aimed to boost organ donation in the US.
  • Concerns exist regarding the ODBC's impact on organ procurement organizations' (OPOs) donation conversion rates.
  • This study evaluated the ODBC's effect on organ donation rates at Carolinas Medical Center (CMC) and its OPO, focusing on minority donors.

Purpose of the Study:

  • To assess the impact of joining the Organ Donation Breakthrough Collaborative (ODBC) on organ donation rates.
  • To analyze organ donation and consent trends by race and institution.
  • To identify specific institutional or racial disparities in organ donation consent.

Main Methods:

  • Retrospective review of a local organ procurement organization's patient referral database (2002-2010).
  • Calculation and analysis of organ donation approach and consent rates stratified by race and institution.
  • Statistical analysis using chi-square, Fisher exact, and Cochran-Armitage trend tests.

Main Results:

  • Overall approach rate was 13.4% and consent rate was 57.6% across 10,855 screened patients.
  • A temporary increase in approach and consent rates began in 2004 but was not sustained.
  • Consent rates were higher for white patients than for Black and Hispanic patients; only CMC saw a significant increase in consent rates (P = .02), specifically among white patients.

Conclusions:

  • Joining the ODBC led to increased consent rates at CMC but not across other hospitals or for minority groups.
  • Sustained increases in organ donation consent rates require targeted strategies.
  • Enhanced focus is needed to improve consent rates for all racial groups, particularly minority populations.