Related Experiment Video
Updated: May 14, 2026

Visualization of Gut Microbiota-host Interactions via Fluorescence In Situ Hybridization, Lectin Staining, and Imaging
Published on: July 9, 2021
Dyeing to learn more about the gut microbiota
Mohamed S Donia1, Michael A Fischbach
1Department of Bioengineering and Therapeutic Sciences and the California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94158, USA.
Researchers used fluorescence-activated cell sorting (FACS) for high-throughput analysis of gut microbiota function. This method advances microbial community profiling beyond traditional culture-based techniques.
Area of Science:
- Microbiology
- Genomics
- Bioinformatics
Background:
- Culture-based methods for microbial enumeration are limited.
- Deep sequencing offers a high-throughput approach to profile microbial communities.
- Understanding gut microbiota function is crucial for host health.
Related Concept Videos
Bacterial Flora of the Large Intestine
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
Microbiota of the Large Intestine
Functions of the Gut Microbiota
Introduction to the Human Microbiota
Microbiota of the Stomach and Small Intestine
Anatomy of the Intestines
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the small...

