Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Cardiac Cycle01:13

The Cardiac Cycle

97.3K
The heart beats rhythmically in a sequence called the cardiac cycle—a rapid coordination of contraction (systole) and relaxation (diastole).
The Process
Electrical signals—sent from the sinoatrial (SA) node in the right atrial wall to the atrioventricular (AV) node between the right atrium and right ventricle—cause both atria to simultaneously contract. When the signal reaches the AV node, it pauses for approximately a tenth of a second, allowing the atria to contract and...
97.3K
Cardiac Cycle01:29

Cardiac Cycle

12.0K
The cardiac cycle refers to the sequence of events that occur in the heart from the beginning of one heartbeat to the next. It's characterized by alternating periods of contraction (systole) and relaxation (diastole) of the heart muscles.
During the cardiac cycle, blood flow through the heart is regulated entirely by changing pressure gradients. This sequence of events begins with the heart in a state of total relaxation, known as mid-to-late diastole, during which blood passively flows from...
12.0K
Physiology of the Heart: The Cardiac Cycle01:18

Physiology of the Heart: The Cardiac Cycle

7.7K
The cardiac cycle describes the events from one heartbeat to the next. It includes three main phases: diastole, atrial systole, and ventricular systole, all driven by changes in chamber pressures and the function of heart valves.
Diastole: The Relaxation Phase
During diastole, all four heart chambers relax. The atrioventricular (AV) valves open, and the semilunar valves close. This phase sees the lowest chamber pressures, promoting ventricular filling. Venous blood enters the heart through the...
7.7K
Pathophysiology of Cardiac Performance01:29

Pathophysiology of Cardiac Performance

1.3K
Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...
1.3K
Cardiac Output I:Effect of Heart Rate on Cardiac Output01:19

Cardiac Output I:Effect of Heart Rate on Cardiac Output

2.4K
Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart...
2.4K
Pulse01:05

Pulse

3.4K
The pulse is one of the most fundamental physiological indicators of the body's cardiovascular health. It is the rhythmic expansion and contraction of the arterial walls in response to the pressure generated by the heart's pumping action.
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls...
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

SGLT2 Inhibitors in Elderly Patients: Clinical Perspectives from Metabolic and Cardiorenal Protection to Implementation.

Journal of clinical medicine·2026
Same author

Semaglutide for the Silent Phenotype: A Translational Signal in Obesity-Driven HFpEF.

The American journal of cardiology·2026
Same author

In Vitro Tests of Antegrade Distal Limb Perfusion Modalities in Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same author

Baseline PaO2 Modifies the Impact of Oxygenator Use in Temporary Right Ventricular Assist Device Support: A Multicenter Propensity-Weighted Analysis.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same author

ANMCO position paper E-health integration in cardiology clinical care framework.

European heart journal supplements : journal of the European Society of Cardiology·2026
Same author

Evaluation of dual-lumen pulmonary artery cannulation in extracorporeal right ventricular support.

JTCVS open·2026

Related Experiment Video

Updated: Jan 10, 2026

Functional Assessment of the Donor Heart During Ex Situ Perfusion: Insights from Pressure-Volume Loops and Surface Echocardiography
08:21

Functional Assessment of the Donor Heart During Ex Situ Perfusion: Insights from Pressure-Volume Loops and Surface Echocardiography

Published on: October 11, 2022

2.5K

Cardiac cycle efficiency during counterpulsation

Sandro Gelsomino, Salvatore Mario Romano

    The Journal of Thoracic and Cardiovascular Surgery
    |February 19, 2013
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine
    12:37

    Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine

    Published on: February 9, 2016

    13.8K
    Cardiac Catheterization in Mice to Measure the Pressure Volume Relationship: Investigating the Bowditch Effect
    07:38

    Cardiac Catheterization in Mice to Measure the Pressure Volume Relationship: Investigating the Bowditch Effect

    Published on: June 14, 2015

    18.7K

    Related Experiment Videos

    Last Updated: Jan 10, 2026

    Functional Assessment of the Donor Heart During Ex Situ Perfusion: Insights from Pressure-Volume Loops and Surface Echocardiography
    08:21

    Functional Assessment of the Donor Heart During Ex Situ Perfusion: Insights from Pressure-Volume Loops and Surface Echocardiography

    Published on: October 11, 2022

    2.5K
    Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine
    12:37

    Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine

    Published on: February 9, 2016

    13.8K
    Cardiac Catheterization in Mice to Measure the Pressure Volume Relationship: Investigating the Bowditch Effect
    07:38

    Cardiac Catheterization in Mice to Measure the Pressure Volume Relationship: Investigating the Bowditch Effect

    Published on: June 14, 2015

    18.7K