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[Sequential antibiotic therapy in complicated acute appendicitis]

José Carlos Bueno-Rodríguez1, Elizabeth Hernández-Moore, Dayamnelis Aguilar-Atanay

  • 1Hospital Pediátrico Provincial Docente Dr. Eduardo Agramonte Piña, Camagüey, Cuba. jcbueno2010@yahoo.es

Cirugia Y Cirujanos
|February 19, 2013
PubMed

Insights

Sequential postoperative antibiotics in children with complicated appendicitis significantly reduce hospital stays and costs. This approach offers a more efficient and economical treatment strategy for pediatric patients.

Area of Science:

  • Pediatric Surgery
  • Infectious Diseases
  • Pharmacology

Context:

  • Complicated appendicitis in children often requires appendectomy followed by intravenous antibiotics.
  • Current treatment protocols involve prolonged parenteral antibiotic use.
  • There is a need for more efficient and cost-effective postoperative antibiotic strategies.

Purpose:

  • To evaluate the feasibility and outcomes of using sequential intravenous (IV) and oral antibiotics post-appendectomy in pediatric complicated appendicitis.
  • To compare the length of hospital stay and treatment costs between sequential and conventional antibiotic regimens.

Summary:

  • A controlled clinical trial involved 27 children with complicated appendicitis. Twelve received sequential IV-then-oral antibiotics, while 15 had conventional treatment.
  • The sequential group experienced a shorter hospital stay (3.61 days) compared to the conventional group (6.86 days).
  • Treatment costs were substantially lower in the sequential antibiotic group ($256.56 USD) versus the conventional group ($581.99 USD increase).

Impact:

  • Sequential postoperative antibiotic therapy can reduce hospital length of stay in pediatric appendicitis.
  • This approach offers significant cost savings in the management of complicated appendicitis.
  • Findings support the potential for optimizing antibiotic use in pediatric surgical infections.
Abstract

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