Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
Forced Transdifferentiation01:28

Forced Transdifferentiation

Transdifferentiation, also known as lineage reprogramming, was first discovered by Selman and Kafatos in 1974 in silkmoths. They observed that the moths’ cuticle-producing cells transformed into salt-producing cells. Many such cases of natural transdifferentiation occur in organisms. In humans, pancreatic alpha cells can become beta cells. In newts, the loss of the eye’s lens causes the pigmented epithelial cells to transdifferentiate into the lens cells.
Artificial transdifferentiation occurs...
Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular cells,...
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Source And Potency Of Stem Cells01:27

Source And Potency Of Stem Cells

Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Photobiomodulation and electro-stimulation for enhanced healing of hard-to-heal wounds: a literature review.

Journal of wound care·2026
Same author

Artificial Intelligence in Breast Reconstruction: A Scoping Review of Pre-, Intra-, and Postoperative Applications.

Plastic and reconstructive surgery. Global open·2026
Same author

Forehead Eyebrow Lift Techniques: Review of the Literature and Critical Appraisal of Long-term Efficacy.

Plastic and reconstructive surgery. Global open·2026
Same author

Reconstruction of Back Defect from Giant Congenital Melanocytic Nevus Using Dermal Substitute Matrix.

Plastic and reconstructive surgery. Global open·2025
Same author

Lip Augmentation with Soft Tissue Fillers: Social Media, Perceptual Adaptation, and Shifting Beauty Trends beyond Golden Standard Ideals.

Plastic and reconstructive surgery. Global open·2024
Same author

Use of Dermal Substitute Matrices for Coverage of Exposed Limb Vascular Repairs: A Literature Review.

Plastic and reconstructive surgery. Global open·2024

Related Experiment Video

Updated: May 14, 2026

Facial Transplants in Xenopus laevis Embryos
09:08

Facial Transplants in Xenopus laevis Embryos

Published on: March 26, 2014

Stem cell facelift: between reality and fiction.

Bishara S Atiyeh1, Amir E Ibrahim, Dibo A Saad

  • 1American University of Beirut Medical Center, Department of Surgery, Division of Plastic, Reconstructive and Aesthetic Surgery, Beirut, Lebanon.

Aesthetic Surgery Journal
|February 19, 2013
PubMed
Summary
This summary is machine-generated.

The "stem cell facelift" is not a true surgical facelift but rather stem cell-enriched fat grafting for skin tightening. Current evidence does not support claims of complete facial rejuvenation from this procedure.

More Related Videos

Generating iPS Cells from MEFS through Forced Expression of Sox-2, Oct-4, c-Myc, and Klf4
13:02

Generating iPS Cells from MEFS through Forced Expression of Sox-2, Oct-4, c-Myc, and Klf4

Published on: April 7, 2008

Isolation of Adult Human Dermal Fibroblasts from Abdominal Skin and Generation of Induced Pluripotent Stem Cells Using a Non-Integrating Method
10:52

Isolation of Adult Human Dermal Fibroblasts from Abdominal Skin and Generation of Induced Pluripotent Stem Cells Using a Non-Integrating Method

Published on: January 19, 2020

Related Experiment Videos

Last Updated: May 14, 2026

Facial Transplants in Xenopus laevis Embryos
09:08

Facial Transplants in Xenopus laevis Embryos

Published on: March 26, 2014

Generating iPS Cells from MEFS through Forced Expression of Sox-2, Oct-4, c-Myc, and Klf4
13:02

Generating iPS Cells from MEFS through Forced Expression of Sox-2, Oct-4, c-Myc, and Klf4

Published on: April 7, 2008

Isolation of Adult Human Dermal Fibroblasts from Abdominal Skin and Generation of Induced Pluripotent Stem Cells Using a Non-Integrating Method
10:52

Isolation of Adult Human Dermal Fibroblasts from Abdominal Skin and Generation of Induced Pluripotent Stem Cells Using a Non-Integrating Method

Published on: January 19, 2020

Area of Science:

  • Regenerative Medicine
  • Plastic Surgery
  • Dermatology

Background:

  • Stem cell applications are expanding in medical technology, including cosmetic procedures.
  • The
  • The term
  • stem cell facelift
  • is a new marketing phrase in plastic surgery for facial rejuvenation.

Purpose of the Study:

  • To evaluate the scientific literature regarding stem cell therapy for facial rejuvenation.
  • To clarify the distinction between advertised
  • stem cell facelifts
  • and actual surgical procedures.

Main Methods:

  • Review of current scientific literature on stem cell therapy in cosmetic facial procedures.
  • Analysis of clinical evidence supporting claims of facial rejuvenation.

Main Results:

  • Available scientific literature indicates stem cell therapy for facial rejuvenation is limited to theoretical skin tightening.
  • The procedure marketed as a
  • stem cell facelift
  • is primarily stem cell-enriched lipofilling.
  • Clinical evidence does not substantiate claims of complete facial rejuvenation.

Conclusions:

  • The
  • stem cell facelift
  • cannot be equated to a surgical facelift.
  • Promoting this procedure as a complete facial rejuvenation surgery is unethical given current evidence.