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Related Experiment Video

Updated: May 14, 2026

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Published on: January 30, 2020

Three-dimensional and multienergy gamma-ray simultaneous imaging by using a Si/CdTe Compton camera.

Yoshiyuki Suzuki¹, Mitsutaka Yamaguchi, Hirokazu Odaka

¹Department of Radiation Oncology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511, Japan.

|February 19, 2013

Summary

This study developed a silicon/cadmium telluride Compton camera for 3D biomedical imaging. The camera successfully visualized multiple radioisotope distributions in ex vivo and in vivo rat models, demonstrating its multinuclear imaging capability.

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Cerenkov Luminescence Imaging of Interscapular Brown Adipose Tissue

Cerenkov Luminescence Imaging of Interscapular Brown Adipose Tissue

Published on: October 7, 2014

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Last Updated: May 14, 2026

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Published on: January 30, 2020

Cerenkov Luminescence Imaging of Interscapular Brown Adipose Tissue

Cerenkov Luminescence Imaging of Interscapular Brown Adipose Tissue

Published on: October 7, 2014

Area of Science:

Medical Imaging
Nuclear Medicine
Semiconductor Detectors

Background:

Astrophysical observation technologies can be adapted for biomedical imaging.
Compton cameras offer potential for 3D imaging of radioisotope distribution.

Purpose of the Study:

To develop a silicon (Si) and cadmium telluride (CdTe) Compton camera for biomedical applications.
To evaluate the camera's capability for three-dimensional (3D) imaging of multiple radioisotopes.

Main Methods:

Utilized Si/CdTe detector technology adapted from astrophysics.
Employed ex vivo and in vivo rat models with various radioisotopes (FDG, 131I, 67Ga, 111In, 64Cu).
Applied list-mode expectation-maximization-maximum-likelihood algorithm for 3D reconstruction.

Main Results:

Successfully achieved 3D multinuclear imaging, distinguishing distributions of multiple radioisotopes.
Demonstrated clear separation of FDG, 131I-methylnorcholestenol, and 67Ga-citrate in ex vivo models.
Visualized 131I-methylnorcholestenol and 64Cu-chloride distributions in vivo, highlighting differences.

Conclusions:

The Si/CdTe Compton camera effectively resolves multiple isotope distributions in 3D.
Simultaneous multinuclear imaging is achievable with this Compton camera technology in ex vivo settings.