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Updated: May 14, 2026

Generation of Alginate Microspheres for Biomedical Applications
Published on: August 12, 2012
Product standardisation as a tool to control prescribing costs - a case study of alginate liquid preparations
Ola G Alahdab1, Grainne Crealey, Michael G Scott
1Clinical and Practice Research Group (CPRG), School of Pharmacy, Queen's University, Belfast, UK.
Introduction:
Product standardisation involves promoting the prescribing of pre-selected products within a particular category across a healthcare region and is designed to improve patient safety by promoting continuity of medicine use across the primary/secondary care interface, in addition to cost containment without compromising clinical care (i.e. maintaining safety and efficacy).
Objectives:
To examine the impact of product standardisation on the prescribing of compound alginate preparations within primary care in Northern Ireland.
Methods:
Data were obtained on alginate prescribing from the Northern Ireland Central Services Agency (Prescription Pricing Branch), covering a period of 43 months. Two standardisation promotion interventions were carried out at months 18 and 33. In addition to conventional statistical analyses, a simple interrupted time series analysis approach, using graphical interpretation, was used to facilitate interpretation of the data.
Results:
There was a significant increase in the prescribed share of the preferred alginate product in each of the four health boards in Northern Ireland and a decrease in the cost per Defined Daily Dose for alginate liquid preparations overall. Compliance with the standardisation policy was, however, incomplete and was influenced to a marked degree by the activities of the pharmaceutical industry. The overall economic impact of the prescribing changes during the study was small (3.1%).
Conclusion:
The findings suggested that product standardisation significantly influenced the prescribing pattern for compound alginate liquid preparations within primary care across Northern Ireland.
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