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Bronchopulmonary dysplasia: a review

Zarqa Ali1, Peter Schmidt, James Dodd

  • 1University Department of Pediatrics, Section 531, Hvidovre Hospital, Kettegaard Alle, DK-2650 Hvidovre, Copenhagen, Denmark. zarqa_ali@hotmail.com

Archives of Gynecology and Obstetrics
|February 20, 2013
PubMed

Insights

Bronchopulmonary dysplasia (BPD) is a common complication in preterm infants, and its incidence is rising. While treatments exist, none have halted the increasing rates of this condition.

Area of Science:

  • Neonatal Medicine
  • Pediatric Pulmonology

Background:

  • Bronchopulmonary dysplasia (BPD) is a prevalent complication in preterm infants.
  • Increased survival rates of extremely preterm infants contribute to rising BPD prevalence.
  • BPD significantly impacts long-term respiratory health in survivors.

Purpose of the Study:

  • To review the current understanding of bronchopulmonary dysplasia (BPD) etiology and treatment.
  • To assess the impact of existing treatment modalities on BPD incidence.

Main Methods:

  • Systematic literature review was employed.
  • Analysis of existing research on BPD causes and interventions.

Main Results:

  • The etiology of BPD is multifactorial, with prematurity being a prerequisite.
  • Various treatment modalities have been developed over time.
  • Some treatments have lessened BPD severity but not impacted its increasing incidence.

Conclusions:

  • Prematurity is essential for BPD development.
  • Despite therapeutic advancements, the rising incidence of BPD remains a significant challenge.
  • Further research is needed to identify interventions that can reduce BPD rates.
Abstract

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