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Published on: August 14, 2019
New dimeric phenanthrene and flavone from Spiranthes sinensis.
Cong-Ying Li1, Jing Liu, Xue-Hui Su
1Department of Pharmaceutics and Bioengineering , School of Chemical Engineering, Sichuan University, Chengdu 610065, China.
Journal of Asian Natural Products Research
|February 21, 2013
Summary
Researchers isolated a novel dimeric phenanthrene and a new flavone from Spiranthes sinensis. These compounds, along with three known flavonoids, were identified using advanced spectroscopic techniques.
Area of Science:
- Natural Product Chemistry
- Phytochemistry
- Organic Chemistry
Background:
- Spiranthes sinensis is a plant species with potential medicinal properties.
- Phytochemical investigations aim to discover bioactive compounds from natural sources.
Purpose of the Study:
- To isolate and characterize novel and known chemical constituents from the whole plant of Spiranthes sinensis.
- To expand the understanding of the phytochemical profile of this plant species.
Main Methods:
- Isolation of compounds using chromatographic techniques.
- Structure elucidation employing 1D and 2D Nuclear Magnetic Resonance (NMR) spectroscopy, including NOESY, HSQC, and HMBC experiments.
- High-resolution time-of-flight mass spectrometry (HR-TOF-MS) for accurate mass determination.
Main Results:
- Isolation of one novel dimeric phenanthrene: 2,2'-dihydroxy-5,5',7,7'-tetramethoxy-9,9',10,10'-tetrahydro-3,3'-biphenanthrene.
- Isolation of one new flavone: 5-hydroxy-3,7-dimethoxy-4'-(1-hydroxy-3-methylbut-3-en-2-yloxy)-flavone.
- Identification of three additional known flavonoids, reported for the first time in Spiranthes sinensis.
Conclusions:
- The study successfully identified novel and known compounds from Spiranthes sinensis.
- The findings contribute to the phytochemical knowledge of the Spiranthes genus.
- Advanced spectroscopic methods were crucial for the accurate structural determination of the isolated compounds.
