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Updated: May 14, 2026

Characterization of Adipocyte-Derived Extracellular Vesicle Secretion Using a CD63-GFP Reporter Mouse Model In Vivo and In Vitro
Published on: December 5, 2025
Adipokines in obesity
Viviane de Oliveira Leal1, Denise Mafra
1Graduate Program in Medical Sciences, Faculdade de Nutrição, Federal Fluminense University (UFF), Niterói, Brazil. vivianeoleal@yahoo.com.br
Abstract:
White adipose tissue is recognized as a dynamic endocrine organ able to produce and release several bioactive polypeptides known as adipokines. Obesity is defined as an excessive growth of adipose tissue. As such, it is likely that adipokines could play an important role in the development of diseases associated with obesity including insulin resistance, inflammation, hypertension, cardiovascular risk and metabolic disorders. This review focuses on obesity specific-adipokine profiles and the role of some adipokines in obesity-related metabolic disorders.
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