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Updated: May 14, 2026

Single-cell Gene Expression Profiling Using FACS and qPCR with Internal Standards
Published on: February 25, 2017
Quantum combinatorial model of gene expression
Monendra Grover1, Ritu Grover, Rakesh Singh
1National Bureau of Plant Genetic Resources, Pusa Campus, New Delhi, India ; Amity Institute of Biotechnology, Amity University, NOIDA, India.
DNA in chromatin acts as a dynamic library, forming new structures through reversible processes and quantum tunneling. RNA polymerase scans these states, with quantum coherence potentially maintained by screening or decoherence-free subspaces, possibly involving superconductivity.
Area of Science:
- Molecular Biology
- Quantum Physics
- Biophysics
Background:
- Chromatin structure and DNA organization are crucial for cellular processes.
- Understanding DNA's dynamic behavior at the molecular level is an ongoing challenge.
- The role of quantum phenomena in biological systems is an emerging area of research.
Purpose of the Study:
- To propose a novel model for DNA within chromatin as a dynamic combinatorial library.
- To explore the potential involvement of quantum tunneling in linking DNA states.
- To investigate mechanisms for sustaining quantum coherence in biological systems.
Main Methods:
- Theoretical modeling of DNA as a combinatorial library.
- Hypothesizing quantum tunneling for state linkage.
- Discussing quantum coherence maintenance strategies (screening, decoherence-free subspaces).
- Considering the role of superconductivity in avoiding decoherence.
Main Results:
- DNA in chromatin can be viewed as a dynamic library capable of forming novel structures reversibly.
- Quantum tunneling may link different states within this DNA library.
- Mechanisms like screening and decoherence-free subspaces could sustain quantum coherence.
- Superconductivity is proposed as a potential factor in maintaining coherence.
Conclusions:
- The proposed model offers a new perspective on DNA's functional dynamics within chromatin.
- Quantum phenomena, including tunneling and coherence, may play a significant role in biological information processing.
- Further research is needed to experimentally validate the role of quantum effects in DNA organization and function.
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