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Related Concept Videos

Combinatorial Gene Control02:33

Combinatorial Gene Control

Combinatorial gene control is the synergistic action of several transcriptional factors to regulate the expression of a single gene. The absence of one or more of these factors may lead to a significant difference in the level of gene expression or repression.
The expression of more than 30,000 genes is controlled by approximately 2000-3000 transcription factors. This is possible because a single transcription factor can recognize more than one regulatory sequence. The specificity in gene...
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Genetic Information Flows from DNA to RNA to Protein
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What is Gene Expression?01:36

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A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is comprised  of nucleotides and proteins are comprised of amino acids, a mediator is required to convert the information encoded in DNA into proteins. This mediator is the messenger RNA (mRNA). mRNA copies the blueprint from DNA by a process called transcription. In eukaryotes, transcription occurs in the nucleus by complementary base-pairing with the DNA template. The mRNA is then processed and...
What is Gene Expression?01:42

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Updated: May 14, 2026

Single-cell Gene Expression Profiling Using FACS and qPCR with Internal Standards
10:50

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Published on: February 25, 2017

Quantum combinatorial model of gene expression.

Monendra Grover1, Ritu Grover, Rakesh Singh

  • 1National Bureau of Plant Genetic Resources, Pusa Campus, New Delhi, India ; Amity Institute of Biotechnology, Amity University, NOIDA, India.

Bioinformation
|February 21, 2013
PubMed
Summary
This summary is machine-generated.

DNA in chromatin acts as a dynamic library, forming new structures through reversible processes and quantum tunneling. RNA polymerase scans these states, with quantum coherence potentially maintained by screening or decoherence-free subspaces, possibly involving superconductivity.

Keywords:
DecoherenceSuperconductivityTautomeric

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Area of Science:

  • Molecular Biology
  • Quantum Physics
  • Biophysics

Background:

  • Chromatin structure and DNA organization are crucial for cellular processes.
  • Understanding DNA's dynamic behavior at the molecular level is an ongoing challenge.
  • The role of quantum phenomena in biological systems is an emerging area of research.

Purpose of the Study:

  • To propose a novel model for DNA within chromatin as a dynamic combinatorial library.
  • To explore the potential involvement of quantum tunneling in linking DNA states.
  • To investigate mechanisms for sustaining quantum coherence in biological systems.

Main Methods:

  • Theoretical modeling of DNA as a combinatorial library.
  • Hypothesizing quantum tunneling for state linkage.
  • Discussing quantum coherence maintenance strategies (screening, decoherence-free subspaces).
  • Considering the role of superconductivity in avoiding decoherence.

Main Results:

  • DNA in chromatin can be viewed as a dynamic library capable of forming novel structures reversibly.
  • Quantum tunneling may link different states within this DNA library.
  • Mechanisms like screening and decoherence-free subspaces could sustain quantum coherence.
  • Superconductivity is proposed as a potential factor in maintaining coherence.

Conclusions:

  • The proposed model offers a new perspective on DNA's functional dynamics within chromatin.
  • Quantum phenomena, including tunneling and coherence, may play a significant role in biological information processing.
  • Further research is needed to experimentally validate the role of quantum effects in DNA organization and function.