Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Multipotency of Hematopoietic Stem Cells01:19

Multipotency of Hematopoietic Stem Cells

The hematopoietic stem cells or HSCs are multipotent, meaning they can differentiate and give rise to all blood and immune cells. HSCs are maintained in the quiescent stage until an external stimulus initiates their differentiation. The multipotent HSCs exist as two heterogeneous populations, long-term repopulating cells (LTRC) and short-term repopulating cells (STRC). The two HSC populations have different surface markers or receptors and are classified based on quiescence and long-term...
Induced Pluripotent Stem Cells01:06

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic cells are...
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Source And Potency Of Stem Cells01:27

Source And Potency Of Stem Cells

Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
Embryonic Stem Cells00:58

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spatially resolved single-cell analyses of human meningioma identify novel cell states influencing tumor microenvironment and progression.

Nature genetics·2026
Same author

Deep learning for H&E-based meningioma molecular classification and outcome prediction: a retrospective cohort study.

The Lancet. Digital health·2026
Same author

Reirradiation for Patients With Recurrent Ependymoma Across the Age Spectrum.

Advances in radiation oncology·2026
Same author

Modern molecular profiling recontextualizes the NRG/RTOG 0539 trial and reveals hidden high-risk and radiotherapy-resistant meningiomas.

Neuro-oncology·2026
Same author

Adaptation and validation of the cancer awareness measure tool for individuals with intellectual disabilities in Hungary.

Frontiers in public health·2026
Same author

DNA methylation profiling in central nervous system tumours.

Journal of neurology, neurosurgery, and psychiatry·2026

Related Experiment Video

Updated: May 14, 2026

Growing Neural Stem Cells from Conventional and Nonconventional Regions of the Adult Rodent Brain
11:27

Growing Neural Stem Cells from Conventional and Nonconventional Regions of the Adult Rodent Brain

Published on: November 18, 2013

Pituitary stem cells: candidates and implications.

Farshad Nassiri1, Michael Cusimano, Jeff A Zuccato

  • 1Division of Neurosurgery, Department of Surgery, University of Toronto, 30 Bond Street, Toronto, ON, M5B 1W8, Canada. farshad.nassiri@mail.utoronto.ca

Pituitary
|February 21, 2013
PubMed
Summary
This summary is machine-generated.

Pituitary stem cells are crucial for endocrine gland development and function. Research is exploring various cell types to identify the definitive source of these vital stem cells.

More Related Videos

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology
09:48

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology

Published on: February 25, 2022

An Enzyme- and Serum-free Neural Stem Cell Culture Model for EMT Investigation Suited for Drug Discovery
07:43

An Enzyme- and Serum-free Neural Stem Cell Culture Model for EMT Investigation Suited for Drug Discovery

Published on: August 23, 2016

Related Experiment Videos

Last Updated: May 14, 2026

Growing Neural Stem Cells from Conventional and Nonconventional Regions of the Adult Rodent Brain
11:27

Growing Neural Stem Cells from Conventional and Nonconventional Regions of the Adult Rodent Brain

Published on: November 18, 2013

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology
09:48

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology

Published on: February 25, 2022

An Enzyme- and Serum-free Neural Stem Cell Culture Model for EMT Investigation Suited for Drug Discovery
07:43

An Enzyme- and Serum-free Neural Stem Cell Culture Model for EMT Investigation Suited for Drug Discovery

Published on: August 23, 2016

Area of Science:

  • Endocrinology
  • Stem Cell Biology
  • Developmental Biology

Background:

  • The pituitary gland, a master endocrine regulator, undergoes significant postnatal development.
  • Pituitary stem cells are hypothesized to mediate these developmental changes.
  • Defining pituitary stem cells is essential for understanding gland function and regeneration.

Purpose of the Study:

  • To review the evidence for potential pituitary stem cell sources.
  • To discuss the characteristics of stem cells relevant to the pituitary.
  • To explore the implications of identifying a definitive pituitary stem cell type.

Main Methods:

  • Literature review of studies investigating pituitary cell differentiation and stem cell markers.
  • Analysis of candidate cell populations based on stem cell criteria (pluripotency, self-renewal, lack of specialization).
  • Discussion of the functional and developmental significance of identified cell types.

Main Results:

  • Pituitary stem cells lack association with a single specific cell type, unlike neural stem cells.
  • Several major cell types are considered potential sources of pituitary stem cells.
  • Evidence for each candidate source is critically evaluated.

Conclusions:

  • Identifying the definitive pituitary stem cell type remains an ongoing challenge.
  • Understanding pituitary stem cell origins is critical for regenerative medicine and treating endocrine disorders.
  • Further research is needed to elucidate the precise nature and function of pituitary stem cells.