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Mucosal excision and suturing for obesity and GERD
András Légner1, Kazuto Tsuboi, Rudolf Stadlhuber
11Creighton University School of Medicine, Omaha, NE, USA.
Surgical Innovation
|February 21, 2013
Summary
This study shows that creating scar tissue at the gastroesophageal junction via mucosal excision and suturing is feasible for treating GERD and obesity. This new intraluminal approach shows promise for long-term efficacy.
Area of Science:
- Gastroenterology
- Minimally Invasive Surgery
- Bariatric Surgery
Background:
- Current suture and staple devices for GERD and obesity lack long-term efficacy.
- Novel intraluminal techniques are needed for effective treatment.
Purpose of the Study:
- To assess the feasibility of mucosal excision and full-thickness suture apposition.
- To create scar tissue at the gastroesophageal junction for GERD and obesity treatment.
Main Methods:
- Survival animal experiments were conducted on seven mongrel dogs.
- A mucosal excision device was used to remove tissue at the gastroesophageal junction.
- An intraluminal suturing instrument apposed the excision beds.
Main Results:
- All dogs survived without complications.
- GERD model showed decreased gastroesophageal junction compliance.
- Obesity model demonstrated satisfactory gastric outlet apposition and desired scarring.
Conclusions:
- Adequate gastroesophageal junction scarring can be achieved using this technique.
- This method shows potential for intraluminal treatment of GERD and obesity.
- A clinical pilot study is planned to further evaluate this approach.
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