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Updated: May 14, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
Benzyl N-[(Z)-(1-methyl-2-sulfanyl-propyl-idene)amino]-carbamodithio-ate
Mohammed Khaled Bin Break1, Sachin Mehta, M Ibrahim M Tahir
1School of Pharmacy, University of Nottingham Malaysia Campus, Selangor, Malaysia.
Abstract:
The title compound, C(12)H(16)N(2)S(3), was obtained by the condensation reaction of S-benzyl dithio-carbazate and 3-mercaptobutan-2-one. The phenyl ring and thiol (SH) group are approximately perpendicular [S-C-C-C and N-C-C-S torsion angles = 67.8 (3) and 116.9 (2)°, respectively] to the rest of the mol-ecule. In the crystal, mol-ecules are linked by weak S-H⋯S and N-H⋯S hydrogen bonds, π-π inter-actions between the benzene rings [centroid-centroid distance = 3.823 (2) Å] and C-H⋯π inter-actions.
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