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Updated: May 14, 2026

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
Published on: August 22, 2018
1-Tosyl-4-[2-(trifluoro-meth-yl)benz-yl]piperazine
S Sreenivasa1, H C Anitha, K E Manojkumar
1Department of Studies and Research in Chemistry, Tumkur University, Tumkur, Karnataka 572 103, India.
Abstract:
In the crystal structure of the title compound, C(19)H(21)F(3)N(2)O(2)S, the piperazine ring adopts a chair conformation. The dihedral angles between the mean plane of the piperazine ring and the tosyl and trifluoro-methyl-phenyl rings are 74.52 (3) and 68.30 (2)°, respectively. The sulfonamide N atom deviates from the plane defined by the three attached atoms by 0.327 (1) Å. The crystal structure is stabilized by weak C-H⋯π inter-actions.
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