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[Neuropsychological disorders and childhood epilepsies]

Louis Vallée1

  • 1Service de neuropédiatrie, pôle enfant, hôpital Roger-Salengro, CHRU-université Nord de France, 59037 Lille Cedex, France. louis.vallee@chru-lille.fr

La Revue Du Praticien
|February 22, 2013
PubMed

Insights

Epilepsy in children can lead to cognitive and behavioral deficits due to seizures and medications. Even with good prognosis, subtle impairments may persist, impacting intellectual development.

Area of Science:

  • Neuropsychology
  • Pediatric Neurology
  • Developmental Neuroscience

Context:

  • Epilepsy in children presents complex neuropsychological challenges.
  • Understanding the interplay between epilepsy, its treatment, and child development is crucial.
  • Recurrent seizures and medication side effects significantly impact a child's cognitive and behavioral functioning.

Purpose:

  • To review the neuropsychological consequences of childhood epilepsy.
  • To detail the neurodevelopmental origins and progression of comorbidities.
  • To explore factors contributing to cognitive deficits, including seizure frequency and treatment effects.

Summary:

  • Childhood epilepsy's neuropsychological outcomes depend on epilepsy type, history, and treatment.
  • While many children achieve seizure remission, subtle cognitive and behavioral deficits can emerge.
  • Intractable epilepsy with frequent seizures is a significant risk factor for cognitive impairment and intellectual disabilities.

Impact:

  • Informs clinical practice regarding the long-term monitoring of cognitive and behavioral health in children with epilepsy.
  • Highlights the need for early intervention strategies to mitigate potential intellectual disabilities.
  • Contributes to a deeper understanding of epilepsy's impact on neurodevelopment and lifelong outcomes.

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