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Interrupter resistance changes in children with bronchiolitis
Ozge Yilmaz1, Ayhan Sogut, Senem Alkan
1Celal Bayar Univerity Medical Faculty, Dept. of Pediatric Allergy and Pulmonology, Monisa, Turkey. oyilmaz_76@hotmail.com
Insights
Lung function testing in infants with bronchiolitis is challenging. The interrupter technique effectively measures airway resistance in unsedated young children during and after acute bronchiolitis.
Area of Science:
- Pediatric Pulmonology
- Respiratory Physiology
Background:
- Assessing lung function in infants with bronchiolitis is crucial for treatment but faces challenges like sedation needs and lack of standardization.
- The interrupter technique offers a potential solution for evaluating airway function in this age group.
Purpose of the Study:
- To evaluate lung function changes using the interrupter technique in unsedated wheezing children under three years old during and after acute bronchiolitis.
Main Methods:
- A cohort study enrolled children under three with acute bronchiolitis.
- Interrupter resistance (Rint) measurements were taken using a face mask during and after the acute phase.
- Data on bronchiolitis severity, duration, and hospitalization were recorded.
Main Results:
- A significant decrease in expiratory Rint values was observed after clinical bronchiolitis findings resolved (1.08 vs. 0.80 kPa.L-1.s).
- Flow measurements remained stable, while mouth pressure decreased significantly post-illness.
Conclusions:
- The interrupter technique demonstrated higher airway resistance during acute bronchiolitis in young children.
- Rint measurements can detect changes in airway function in unsedated infants with bronchiolitis in ambulatory settings.
Introduction:
Determination of lung function in children younger than three years with bronchiolitis may aid in treatment; however, technical difficulties such as requirement of sedation and lack in standardization limit clinical use.
Objectives:
Aim of this study was to evaluate lung function changes using the interrupter technique in unsedated wheezing children younger than 3 years during and after acute bronchiolitis.
Methods:
Children with acute bronchiolitis younger than three years age were enrolled in this cohort study. Number of previous bronchiolitis episodes, severity of pulmonary findings, duration of acute bronchiolitis findings before presentation, requirement for hospitalization were recorded during initial enrollment. Duration of the current bronchiolitis was recorded. Interrupter resistance (Rint) measurements were performed on all children during and after bronchiolitis, using a face mask.
Results:
Mean (+/-SD) age of the children enrolled was 9.4 +/- 2.9 months. Mean bronchiolitis score was 5.6 +/- 1.4 at presentation. Mean duration of acute bronchiolitis before and after presentation were 10.1 +/- 13.0 and 5.1 +/- 2.3 days, respectively. There was a significant decrease in expiratory Rint values after clinical bronchiolitis findings terminated [1.08 (0.45) vs. 0.80 (0.33) kPa.L-1.s, p = 0.009]. Flow had not changed significantly while mouth pressure had decreased (p = 0.96 and p = 0.01, respectively).
Conclusion:
Interrupter technique measurements showed higher resistance during acute bronchiolitis in children, which decreased after acute findings, disappeared. Rint may be used as a method to detect the change in airway function in unsedated children younger than three years in ambulatory conditions, despite some limitations of standardization in this age group.
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