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Updated: May 14, 2026
08:49
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
A clinically invisible melanoma.
Eshini Perera1, Nicholas Mellick, Paul Teng
1Department of Dermatology, Queensland Institute of Dermatology, Brisbane, Queensland, Australia.
The Australasian Journal of Dermatology
|February 22, 2013
Summary
This case report details an amelanotic lentigo maligna, a rare skin cancer variant, discovered incidentally. This specific case lacked typical visible or palpable features, highlighting diagnostic challenges.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Amelanotic lentigo maligna is a rare subtype of lentigo maligna.
- It often presents as subtle, erythematous, scaly macules.
- Misdiagnosis as benign dermatoses is common due to its non-specific appearance.
Observation:
- A case of amelanotic lentigo maligna was incidentally identified.
- The patient was an 87-year-old woman.
- This particular lesion exhibited no visible or palpable characteristics.
Findings:
- The amelanotic lentigo maligna was discovered via shave biopsy.
- The absence of typical clinical signs presented a diagnostic challenge.
- This case underscores the variability in presentation of this rare condition.
Implications:
- Highlights the importance of histological examination for diagnosing amelanotic lentigo maligna.
- Suggests that amelanotic lentigo maligna can present without any distinguishing clinical features.
- Emphasizes the need for increased awareness among clinicians regarding subtle presentations of lentigo maligna.
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