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Updated: May 14, 2026

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis
Published on: March 8, 2022
Intravascular metastatic melanoma: a difficult diagnosis
Samer Ghattas1, Julie Howle, Wei Wang
1Department of Nuclear Medicine, PET and Ultrasound, Westmead Hospital, Sydney, New South Wales, Australia. s.ghattas1@gmail.com
Abstract:
Melanoma is a common cancer with the potential for widespread metastasis; however intravascular metastasis is extremely rare. We report an unusual case of a patient with metastatic melanoma in whom (18) F-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) demonstrated an intravascular melanoma metastasis in the superior vena cava (SVC), successfully treated with external beam radiotherapy. To our knowledge, this is the first reported case where FDG PET-CT was used to make this diagnosis.
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