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Related Concept Videos

Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
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Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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Related Experiment Video

Updated: May 14, 2026

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
05:19

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

Active surveillance: oncologic outcome.

Lionne D F Venderbos1, Leonard P Bokhorst, Chris H Bangma

  • 1Department of Urology, Erasmus Medical Center, Rotterdam, The Netherlands. l.venderbos@erasmusmc.nl

Current Opinion in Urology
|February 22, 2013
PubMed
Summary
This summary is machine-generated.

Active surveillance for prostate cancer is safe, with very low mortality rates. Postponing treatment for most men does not compromise oncologic outcomes, avoiding overtreatment.

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A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
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Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
07:29

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

Published on: April 22, 2019

Area of Science:

  • Oncology
  • Urology
  • Men's Health

Background:

  • Active surveillance is an established strategy for managing low-risk prostate cancer.
  • Concerns remain regarding the long-term oncologic outcomes and potential overtreatment with radical therapies.

Purpose of the Study:

  • To review recent literature (12-18 months) on oncologic outcomes for men undergoing active surveillance for prostate cancer.
  • To assess the impact of active surveillance on disease-specific mortality and intermediate outcomes.

Main Methods:

  • Systematic review of recent published trials comparing radical prostatectomy with watchful waiting.
  • Analysis of data on prostate cancer-specific mortality and intermediate outcomes under active surveillance.

Main Results:

  • Radical treatment benefits only a small proportion of men; many are overtreated.
  • Active surveillance aims to postpone treatment for most men while maintaining low disease-specific mortality.
  • Recent data show very low prostate cancer-specific mortality under active surveillance, with similar outcomes to immediate radical treatment.

Conclusions:

  • Active surveillance demonstrates very low prostate cancer-specific mortality, though longer follow-up is needed.
  • Postponing treatment in active surveillance does not appear to negatively impact oncologic outcomes.
  • The majority of men can avoid active treatment without compromising oncologic outcomes.