Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Epilepsy ll: Types01:22

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
Seizures l: Introduction01:20

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
Electroconvulsive Therapy01:30

Electroconvulsive Therapy

Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early years,...
Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Antiepileptic Drugs: Glutamate Antagonists01:14

Antiepileptic Drugs: Glutamate Antagonists

Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A randomized feasibility pilot trial of a remotely delivered physical activity intervention for adults with epilepsy.

Epilepsy & behavior : E&B·2026
Same author

Associations Between Testing and Treatment Pathways in a Case of Pediatric Nonlesional Epilepsy: A Census Survey of NAEC Center Directors.

Journal of child neurology·2024
Same author

Developing optimized physical activity interventions for drug-resistant epilepsy: Challenges and lessons learned from a remote exercise intervention pilot trial.

Epilepsy & behavior reports·2024
Same author

Preclinical toxicity studies supporting 2DG for treatment of status epilepticus.

Epilepsy & behavior : E&B·2024
Same author

Analysis of seizure-cluster circadian periodicity from a long-term, open-label safety study of diazepam nasal spray.

Epilepsia·2024
Same author

Epilepsy monitoring unit practices and safety among NAEC epilepsy centers: A census survey.

Epilepsy & behavior : E&B·2023

Related Experiment Video

Updated: May 14, 2026

Electrophoretic Delivery of γ-aminobutyric Acid (GABA) into Epileptic Focus Prevents Seizures in Mice
07:01

Electrophoretic Delivery of γ-aminobutyric Acid (GABA) into Epileptic Focus Prevents Seizures in Mice

Published on: May 16, 2019

Delivering quality care in epilepsy.

Nathan B Fountain1

  • 1Department of Neurology, University of Virginia, Charlottesville, VA 22908, USA. nbf2p@virginia.edu

Current Opinion in Neurology
|February 22, 2013
PubMed
Summary

Implementing quality measures in epilepsy care is crucial for improving patient outcomes. However, adoption is limited by a lack of high-level evidence and data gaps, necessitating further research and standardization.

More Related Videos

Performing Behavioral Tasks in Subjects with Intracranial Electrodes
12:10

Performing Behavioral Tasks in Subjects with Intracranial Electrodes

Published on: October 2, 2014

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
05:54

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

Published on: June 13, 2016

Related Experiment Videos

Last Updated: May 14, 2026

Electrophoretic Delivery of γ-aminobutyric Acid (GABA) into Epileptic Focus Prevents Seizures in Mice
07:01

Electrophoretic Delivery of γ-aminobutyric Acid (GABA) into Epileptic Focus Prevents Seizures in Mice

Published on: May 16, 2019

Performing Behavioral Tasks in Subjects with Intracranial Electrodes
12:10

Performing Behavioral Tasks in Subjects with Intracranial Electrodes

Published on: October 2, 2014

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
05:54

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

Published on: June 13, 2016

Area of Science:

  • Quality of care science in medicine
  • Epilepsy care quality improvement

Background:

  • Quality of care focuses on implementing population-level policies to enhance medical services.
  • Epilepsy care is increasingly a focus within quality of care initiatives, impacting many patients managed by generalists.

Purpose of the Study:

  • To review the current state and challenges of quality of care in epilepsy.
  • To assess the development and adoption of epilepsy quality performance measures.

Main Methods:

  • Review of recently approved epilepsy quality performance measures.
  • Analysis of reasons for measure adoption or non-adoption by national organizations and Medicare.
  • Examination of evidence supporting epilepsy treatments and identification of care gaps.

Main Results:

  • Eight epilepsy quality measures were approved, but only three by Medicare and one by the National Quality Forum.
  • Lack of high-level evidence is a primary barrier to measure adoption.
  • Evidence exists for epilepsy surgery and new antiepileptic drugs, but care gaps and coding imprecision persist.

Conclusions:

  • Quality measurement in epilepsy care is ongoing and requires healthcare provider engagement.
  • Standardized quality measures can improve epilepsy care if evidence-based, feasible, and address care gaps.