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Updated: May 14, 2026

Experimental Infection of Mice with the Parasitic Nematode Strongyloides ratti
Published on: January 17, 2025
[Disseminated strongyloidosis in AIDS patients: apropos of two cases]
María del C Dorvigny Scull1, Osvaldo Castro, Fidel Angel Núñez
1Instituto de Medicina Tropical Pedro Kouri. mcdorvi@ipk.sld.cu
Abstract:
Two cases with hyperinfection syndrome caused by Strongyloides stercoralis in the development of HIV/AIDS were reported. These patients had a severe immunodepression with lymphocyte counts of the subpopulation of CD4+ T cells under 200 cells/mm3. In the first case, a predominance of respiratory manifestations was observed and numerous Strongyloides rhabditiform larvae were found in sputum and faeces. In the second case, the neurological manifestations were more common, but only a larva of Strongyloides stercoralis could be detected per microscopic field (100X of magnification) in faeces. Both individuals in spite of the applied therapeutics had a fatal end. The importance of this paper is to be aware of the possibility of an infection disseminated by this helminth in some patients, and to be ready for a suitable diagnosis and an adequate treatment or prevention of the fatal consequences of the infection caused by this nematode.
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