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Updated: May 14, 2026

Mouse Kidney Transplantation: Models of Allograft Rejection
Published on: October 11, 2014
Bilateral native kidney neoplasia detected by ultrasound in functionning renal allograft recipient
Annalisa Noce1, Giuseppe Iaria, Olga Durante
1Department of Internal Medicine, Nephrology and Hypertension Unit, University of Rome Tor Vergata, Rome, Italy. annalisa.noce@fastwebnet.it
Abstract:
We report the case of bilateral renal clear cell carcinoma in the native kidney, occurring fouryears after renal transplantation. Renal Doppler duplex sonography revealed large solid bilateral neoformation. Total-body computed tomography confirmed the presence of bilateral kidney lesions and also showed the presence of concomitant gross dyscariocinetic lesion of left hemotorax. The patient underwent bilateral native nephrectomy and the histological diagnosis was renal cell carcinoma. Subsequent left upper lobectomy revealed necrotic keratinizing squamous cell carcinoma. Then, the patients was switched tacrolimus to everolimus treatment and mycophenolate mofetil was reduced.
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