Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Surgical goniosynechialysis for angle-closure glaucoma.

B J Shingleton1, M A Chang, A R Bellows

  • 1Glaucoma Service, Ophthalmic Consultants of Boston, Inc.

Ophthalmology
|May 1, 1990
PubMed
Summary

Surgical goniosynechialysis effectively reduced synechiae and lowered intraocular pressure (IOP) in patients with uncontrolled angle-closure glaucoma. This surgical intervention proved successful in most cases, decreasing medication needs and improving IOP control.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Etramp5 as a useful serological marker in children to assess the immediate effects of mass drug campaigns for malaria.

BMC infectious diseases·2022
Same author

Diffusion-weighted MRI as a screening tool for hepatocellular carcinoma in cirrhotic livers: correlation with explant data-a pilot study.

Abdominal radiology (New York)·2018
Same author

IL-1β induces p62/SQSTM1 and represses androgen receptor expression in prostate cancer cells.

Journal of cellular biochemistry·2014
Same author

Single-source dual-energy spectral multidetector CT of pancreatic adenocarcinoma: optimization of energy level viewing significantly increases lesion contrast.

Clinical radiology·2012
Same author

Glaucoma and intraocular lenses-evolving concepts in implantation and in management of complications.

Journal of glaucoma·2009
Same author

A comparison of the potential acuity meter (PAM) and the illuminated near card (INC) in patients undergoing phacoemulsification.

Eye (London, England)·2005

Area of Science:

  • Ophthalmology
  • Surgical Procedures
  • Glaucoma Management

Background:

  • Synechial angle-closure glaucoma poses a challenge when unresponsive to medical and laser therapies.
  • Surgical intervention is often necessary for advanced cases to prevent vision loss.

Purpose of the Study:

  • To evaluate the efficacy of surgical goniosynechialysis in patients with medically and laser-refractory synechial angle-closure glaucoma.
  • To assess the impact of goniosynechialysis on synechiae reduction, intraocular pressure (IOP), and medication requirements.

Main Methods:

  • Fifteen patients with uncontrolled synechial angle-closure glaucoma underwent surgical goniosynechialysis.
  • Five patients received goniosynechialysis alone; ten had it combined with other surgical procedures.
  • Outcomes measured included synechiae reduction, IOP levels, and medication usage.

Related Experiment Videos

Main Results:

  • Surgical goniosynechialysis successfully reduced synechiae in 93% of eyes (14/15).
  • The mean extent of angle closure significantly decreased from 340° to 80° (P < 0.0001).
  • Mean IOP dropped from 40 mmHg to 14 mmHg (P < 0.0001), with a reduction in glaucoma medications.

Conclusions:

  • Surgical goniosynechialysis is an effective treatment for reducing synechiae and lowering IOP in specific glaucoma cases.
  • The procedure can be performed alone or combined with other surgeries, offering a viable option for refractory angle-closure glaucoma.
  • Early intervention (less than 6 months' duration) appears crucial for optimal outcomes.