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[Targeted therapeutics and their role in the treatment of internal diseases]

P Klener1

  • 1Interní Klinika 1 Lékarské Fakulty UK a VFN a UHKT Praha. Pavel.Klener@ruk.cuni.cz

Vnitrni Lekarstvi
|February 23, 2013
PubMed

Insights

Targeted therapy utilizes known disease pathophysiology and biomarkers for treatment, including monoclonal antibodies and tyrosine-kinase inhibitors. These targeted agents offer a precise approach to managing malignancies by targeting specific cellular or molecular pathways.

Area of Science:

  • Oncology
  • Pharmacology
  • Biomedical Science

Background:

  • Targeted therapy represents a treatment strategy based on understanding disease pathophysiology and biomarkers, primarily for malignancies.
  • Early molecularly targeted agents include monoclonal antibodies and tyrosine-kinase inhibitors.
  • These therapies target specific biomarkers on cancer cells or key molecular pathways involved in cancer progression.

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