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Dioscin Mediated IgA Nephropathy Alleviation by Inhibiting B Cell Activation In Vivo and Decreasing Galactose-Deficient IgA1 Production In Vitro
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[Dapsone-induced decrease in the HbA(1c) level may cause artefacts in diabetic control]

Siv Elisabeth Lajlev1, Søren Andreas Ladefoged, Kjeld Hermansen

  • 1Medicinsk Endokrinologisk Afdeling, Aarhus Universitetshospital, Denmark. siv@lajlev.dk

Ugeskrift for Laeger
|February 23, 2013
PubMed

Insights

Dapsone treatment in a diabetic patient caused a misleading drop in glycated haemoglobin (HbA1c) levels. This occurred due to mild haemolysis, affecting red blood cell lifespan and impacting diabetes monitoring.

Area of Science:

  • Endocrinology
  • Hematology
  • Dermatology

Background:

  • Glycated haemoglobin (HbA1c) is crucial for monitoring diabetes mellitus (DM) and diagnosing type 2 DM.
  • Dapsone is a medication used to treat dermatitis herpetiformis, a condition linked to coeliac disease.

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