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Knowledge map of artemisinin research in SCI and Medline database
Qiang Yao1, Jing Chen, Peng-Hui Lyu
1School of Medicine and Health Management, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Journal of Vector Borne Diseases
|February 23, 2013
Summary
Artemisinin research is rapidly expanding, with key areas including pharmacology and chemistry. Future trends focus on new compound synthesis and understanding mechanisms of action for malaria treatment.
Area of Science:
- Pharmacology & Pharmacy
- Chemistry
- Parasitology
- Tropical Medicine
Background:
- Artemisinin, derived from Artemisia annua, has a long history in traditional Chinese medicine for treating fever and malaria.
- The compound has received significant recognition, including the 2011 Lasker-DeBakey clinical medical research award.
Purpose of the Study:
- To map the global research landscape of artemisinin.
- To identify research trends and provide references for interested researchers.
Main Methods:
- Bibliometric analysis and knowledge visualization techniques were employed.
- Data from Science Citation Index (SCI) and Medline papers were analyzed using Thomson Data Analyzer (TDA), Netdraw, and Aureka software.
- Analysis covered publication outputs, subject categories, journals, countries, international collaboration, citations, authorship, and keywords.
Main Results:
- Global artemisinin research has surged in recent years, with Pharmacology, Pharmacy, and Chemistry as dominant fields.
- The United States leads in paper quantity and quality, while developing nations show high activity but require quality improvement.
- Emerging keywords indicate future research directions in mechanism of action, pharmacokinetics, and artemisinin-based alternatives.
Conclusions:
- Bibliometric analysis predicts future trends in artemisinin research.
- Future research is expected to focus on synthesizing novel active compounds, elucidating mechanisms of action, and developing new combination therapies.
