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Updated: May 14, 2026
Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants
Published on: March 14, 2013
Cerebral near-infrared spectroscopy during transition of healthy term newborns
Munira Almaazmi1, Manuel B Schmid, Stefanie Havers
1Division of Neonatology and Pediatric Intensive Care, Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, Germany.
Background:
Values of regional cerebral tissue oxygen saturation (cStO2) have been described during transition of term and preterm infants after birth. However, use of different devices precludes comparison of measurements.
Objective:
To measure cStO2 during transition of term infants using a calibrated 4-wavelength laser light source near-infrared spectroscopy oximeter (FORE-SIGHT) to obtain data that allow comparison with cStO2 of very-low-birth-weight (VLBW) infants using this oximeter and with cStO2 of term infants using different oximeters.
Methods:
cStO2 (FORE-SIGHT oximeter), preductal arterial oxygen saturation and heart rate were measured in 46 healthy term infants (n = 20 spontaneous delivery, n = 22 caesarean section, n = 4 assisted vaginal delivery) during the first 10 min after delivery.
Results:
The median (interquartile range) cStO2 at 2 min after birth was 42% (39-46) after spontaneous delivery, 42% (30-52) after caesarean section and 36% (20-53) after assisted vaginal delivery (no difference between groups). In association with increasing arterial oxygen saturation and heart rate, cStO2 increased continuously and reached a steady state approximately 8 min after birth of 62-77% (interquartile range) in all three groups.
Conclusions:
Healthy term newborns had similar cStO2 changes from 2 min after birth regardless of the mode of delivery. cStO2 of healthy term infants was lower than cStO2 of VLBW infants during transition. cStO2 values as measured by the FORE-SIGHT oximeter seem in the range of values as measured by the NIRO 300 oximeter. They were lower than values as measured by the INVOS 5100 oximeter.
