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[Thrombosis and obstruction associated with central venous lines. Incidence and risk factors]

A Vivanco Allende1, C Rey Galán, M V Rodríguez de la Rúa

  • 1Sección de Cuidados Intensivos Pediátricos, Área de Gestión Clínica de Pediatría, Hospital Universitario Central de Asturias, Universidad de Oviedo, Oviedo, Asturias, España. anaviall@hotmail.com

Anales De Pediatria (Barcelona, Spain : 2003)
|February 23, 2013
PubMed

Insights

Central venous lines (CVL) in critically ill children frequently cause obstruction and thrombosis. Longer CVL duration is a key risk factor for obstruction, highlighting the need for careful monitoring in pediatric intensive care units.

Area of Science:

  • Pediatric critical care medicine
  • Vascular access devices
  • Clinical epidemiology

Context:

  • Central venous lines (CVL) are essential for managing critically ill children.
  • Complications like thrombosis and obstruction can impede CVL function and patient care.
  • Understanding risk factors is crucial for optimizing CVL use in pediatric intensive care units (PICUs).

Purpose:

  • To determine the incidence of thrombosis and obstruction in CVLs placed in critically ill children.
  • To identify independent risk factors associated with these central venous line complications.

Summary:

  • A prospective observational study analyzed 825 CVLs in 546 pediatric patients.
  • Obstruction occurred in 4.96% and thrombosis in 1.18% per 100 CVLs.
  • CVL duration was the only independent risk factor for obstruction (OR 1.05). Bivariate analysis suggested thrombosis risk with line number and parenteral nutrition.

Impact:

  • Obstruction and thrombosis are common CVL complications in PICUs.
  • Prolonged CVL dwell time is a significant risk factor for obstruction.
  • Findings inform clinical practice to minimize CVL-related complications in pediatric critical care.
Abstract

Keywords:
Catéter venoso centralCentral venous catheterComplicaciónComplicationCuidados intensivosIntensive careObstrucciónObstructionThrombosisTrombosis

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