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Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
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In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis
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Primary epiphyseal Ewing sarcoma: a case report.

Murat Bülbül1, Harzem Özger, Bilge Bilgiç

  • 1Department of Orthopedics and Traumatology, Faculty of Medicine, İstanbul Medipol University, İstanbul, Turkey. muratbulbul@yahoo.com

Acta Orthopaedica Et Traumatologica Turcica
|February 23, 2013
PubMed
Summary
This summary is machine-generated.

This study presents a rare case of Ewing sarcoma found in the epiphysis of a child's bone. It highlights the importance of precise biopsy techniques to minimize complications during treatment.

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Area of Science:

  • Pediatric Oncology
  • Skeletal Tumors
  • Orthopedic Surgery

Background:

  • Ewing sarcoma is a common pediatric bone malignancy.
  • Typically affects the diaphysis and metaphysis of long bones.
  • Epiphyseal involvement is exceptionally rare.

Observation:

  • A unique case of Ewing sarcoma confined to the epiphysis in an immature skeleton.
  • The tumor's unusual location presented diagnostic and surgical challenges.

Findings:

  • Successful diagnosis and management of a rare epiphyseal Ewing sarcoma.
  • Demonstrated the feasibility of biopsy without joint contamination.

Implications:

  • Emphasizes the need for considering rare presentations of Ewing sarcoma.
  • Highlights surgical techniques to reduce joint morbidity in epiphyseal bone tumors.
  • Informs orthopedic oncology regarding management of pediatric bone sarcomas.