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Native aortic valve fungal endocarditis
Shyam Chand Chaudhary1, Kamal Kumar Sawlani, Rahul Arora
1Department of Medicine, KG Medical University (Erstwhile CSMMU), Lucknow, Uttar Pradesh, India. drshyamchandchaudhary@rediffmail.com
Abstract:
Infective endocarditis is the most common and dangerous form of endovascular infection. Fungal endocarditis especially of native valve is rare with Candida albicans being the causative organism in one-fourth of such cases. Diagnosis of such cases is further complicated if blood cultures are sterile, vegetations are not initially seen on echocardiogram and patient presents with non-specific symptoms. We hereby report a patient with native valve fungal endocarditis, treated successfully with voriconazole.
Insights
Fungal endocarditis, a rare but serious infection, can be challenging to diagnose. This case highlights successful treatment of native valve fungal endocarditis with voriconazole.
Area of Science:
- Cardiology
- Infectious Diseases
- Mycology
Background:
- Infective endocarditis is a significant cause of endovascular infection.
- Fungal endocarditis, particularly affecting native valves, is uncommon.
- Candida albicans accounts for approximately 25% of fungal endocarditis cases.
Observation:
- Diagnosis is often difficult due to sterile blood cultures.
- Echocardiograms may not initially detect vegetations.
- Patients frequently present with non-specific symptoms.
Findings:
- This report details a successful treatment of native valve fungal endocarditis.
- Voriconazole was the effective antifungal agent used in this case.
Implications:
- This case underscores the importance of considering fungal endocarditis in complex cases.
- Successful treatment with voriconazole offers a therapeutic option for this rare condition.
- Improved diagnostic strategies for fungal endocarditis are warranted.
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Endocarditis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis III: Medical Management
Endocarditis IV: Nursing Management
Aortic Regurgitation I: Introduction
Mitral Stenosis I: Introduction

