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A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis
09:36

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

Published on: August 12, 2025

Diabetes does not affect outcome of symptomatic carotid stenosis treated with endovascular techniques

Aida Lago1, Vera Parkhutik, Jose Ignacio Tembl

  • 1Department of Neurology, Hospital Universitari la Fe, Valencia, Spain. alagom @ meditex.es

European Neurology
|February 23, 2013
PubMed

Insights

Diabetes does not increase risks for patients undergoing carotid angioplasty and stenting (CAS). This study found similar outcomes for diabetic and non-diabetic patients treated with CAS for carotid stenosis.

Area of Science:

  • Cardiovascular Medicine
  • Endovascular Surgery
  • Diabetology

Background:

  • The impact of diabetes on carotid revascularization outcomes, particularly carotid angioplasty and stenting (CAS), remains debated.
  • Limited data exists on the safety and efficacy of CAS in diabetic patients with carotid stenosis.

Purpose of the Study:

  • To investigate whether diabetes mellitus is a risk factor for adverse outcomes in patients with symptomatic carotid stenosis undergoing CAS.
  • To compare the 30-day and long-term morbidity, mortality, and restenosis rates between diabetic and non-diabetic patients treated with CAS.

Main Methods:

  • A comparative study of 318 patients (116 diabetics) with symptomatic carotid stenosis treated with endovascular techniques.
  • Analysis of 30-day and long-term outcomes, including stroke, ischemic cardiopathy, death, and restenosis rates (≥50%).
  • Follow-up was conducted for a median of 56 months.

Main Results:

  • No significant differences in 30-day (4% vs. 5.2%) or long-term (26.4% vs. 34.3%) stroke and mortality rates between non-diabetic and diabetic patients.
  • Diabetic patients showed a higher incidence of death due to myocardial infarction (44% vs. 17.5%, p=0.04).
  • Restenosis rates (≥50%) were similar between groups (5.9% vs. 7.4%).

Conclusions:

  • Carotid angioplasty and stenting (CAS) is an effective and safe endovascular treatment for diabetic patients with symptomatic carotid stenosis.
  • Diabetes mellitus did not emerge as an independent risk factor for increased complications following CAS in this patient cohort.
Abstract

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