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Successful immunotherapy in life-threatening parvovirus B19 infection in a child

Marine Butin1, Yahia Mekki, Alice Phan

  • 1Service de Néphrologie, Dermatologie et Rhumatologie Pédiatrique, HFME, Hôpital Louis Pradel, Bron, France.

The Pediatric Infectious Disease Journal
|February 23, 2013
PubMed

We report a case of an immunocompetent child who developed parvovirus B19 infection complicated by autoinflammatory disease with myocarditis, tamponade and macrophage activation syndrome. He recovered with immunotherapy including prednisone, immunoglobulins, cyclosporin and anakinra (anti-interleukin-1). The report shows that parvovirus can provoke severe systemic inflammation with acute heart injury and that anti-interleukin-1 might be considered in such parvovirus-related inflammation.

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