Related Experiment Video
Updated: May 14, 2026

Characterization of Vascular Morphology of Neovascular Age-Related Macular Degeneration by Indocyanine Green Angiography
Published on: August 11, 2023
Combination therapy for the treatment of neovascular age-related macular degeneration
Miriam Englander1, Peter K Kaiser
1Cole Eye Institute, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Purpose Of Review:
To discuss the current combination treatments that involve existing as well as novel drugs that show promise for the treatment of neovascular age-related macular degeneration.
Recent Findings:
Photodynamic therapy in combination with antivascular endothelial growth factor (VEGF) and steroids is currently used as a second-line therapy in patients not responding to monotherapy with anti-VEGF agents or in whom the treatment burden of monthly injections is too great. It is used as a primary therapy for idiopathic polypoidal choroidal vasculopathy. Radiation and antiplatelet-derived growth factor therapy show promising results and are currently under investigation.
Summary:
Using combination treatments that target other pathways involved in angiogenesis will hopefully improve on the results of current anti-VEGF agents and may result in greater visual improvement and more convenient dosing regimens.
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