Related Experiment Video
Updated: May 14, 2026

09:04
Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
Published on: March 7, 2025
Reading the tea leaves of tumor-mediated immunosuppression
1Pediatric Oncology Branch, National Cancer Institute, CCR, NIH, Bethesda, Maryland 20892, USA. Rimas.Orentas@nih.gov
Abstract:
Polyphenol E, available as Polyphenon E, is a green tea extract whose activity can be benchmarked to the presence of specific catechins such as epigallocatechin 3-gallate (EGCG). Herein, Polyphenon E is shown to reverse myeloid-derived suppressor cell activity, linking the activity of a natural product extract to cell-mediated immunity.
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