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Fetal cystic hygromata: insights gained from fetal blood sampling
Y Tannirandorn1, U Nicolini, P C Nicolaidis
1Royal Postgraduate Medical School, Institute of Obstetrics and Gynecology, Queen Charlotte's Chelsea Hospital, London, U.K.
Prenatal Diagnosis
|March 1, 1990
Abstract:
Twelve second-trimester fetuses with cystic hygroma underwent fetal blood sampling for rapid karyotyping, haematologic evaluation, and blood gas analysis. An abnormal karyotype was found in seven cases: monosomy X in five, trisomy 21 in one, and trisomy 13 in the other. Eight of ten fetuses undergoing blood gas analysis showed hypoxaemia, five of which were growth-retarded. Nine pregnancies were terminated. Of the remaining three, only one fetus survived the perinatal period.