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Related Concept Videos

Pneumothorax-II01:27

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Atelectasis II: Pathophysiology01:10

Atelectasis II: Pathophysiology

Atelectasis develops when alveoli lose their air and collapse inward. Because lung tissue is naturally elastic, these air sacs shrink rather than remaining open. Collapsed alveoli are no longer ventilated, reducing their role in gas exchange. Blood flow may continue in these regions, creating a ventilation–perfusion mismatch. Clinical findings include decreased breath sounds, dullness to percussion, reduced chest expansion, and decreased tactile fremitus as sound transmission through collapsed...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Chronic Obstructive Pulmonary Disease II: Emphysema01:23

Chronic Obstructive Pulmonary Disease II: Emphysema

Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.
Pleural Disorders: Types and Brief Description01:30

Pleural Disorders: Types and Brief Description

The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
Endoscopic Studies I: Bronchoscopy and Thoracoscopy01:30

Endoscopic Studies I: Bronchoscopy and Thoracoscopy

Endoscopy is a non-surgical medical technique used to examine a person's internal organs and vessels. This lesson will focus on two types of endoscopic studies: bronchoscopy and thoracoscopy.
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due to...

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Related Experiment Video

Updated: May 14, 2026

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome
07:27

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Published on: January 23, 2026

Changes in lung function after surgery for mesothelioma.

Till Ploenes1, Thomas Osei-Agyemang, Alexander Krohn

  • 1Department of Thoracic Surgery, University Medical Center Freiburg, Freiburg, Germany. Till.Ploenes@uniklinik-freiburg.de

Asian Cardiovascular & Thoracic Annals
|February 23, 2013
PubMed
Summary
This summary is machine-generated.

Pleurectomy/decortication preserves pulmonary function in mesothelioma patients. Extrapleural pleuropneumonectomy significantly impairs lung function, potentially causing dyspnea and affecting quality of life.

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A Standardized Method for Measuring Internal Lung Surface Area via Mouse Pneumonectomy and Prosthesis Implantation
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Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome
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A Standardized Method for Measuring Internal Lung Surface Area via Mouse Pneumonectomy and Prosthesis Implantation
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Published on: July 26, 2017

Area of Science:

  • Thoracic surgery
  • Pulmonary medicine
  • Oncology

Background:

  • The impact of surgical interventions like pleurectomy/decortication and extrapleural pleuropneumonectomy on pulmonary function remains unevaluated.
  • Malignant pleural mesothelioma necessitates surgical treatment, highlighting the need to understand functional outcomes.

Purpose of the Study:

  • To assess and compare pulmonary function parameters before and after pleurectomy/decortication versus extrapleural pleuropneumonectomy.
  • To determine the functional consequences of different surgical approaches for unilateral malignant pleural mesothelioma.

Main Methods:

  • Retrospective review of 48 patients with unilateral malignant pleural mesothelioma.
  • Data collection included medical history, histology, survival, and pre- and postoperative pulmonary function tests.
  • Information was gathered from a university medical database and patient/physician interviews.

Main Results:

  • Pulmonary function remained stable post-pleurectomy/decortication (23 patients).
  • Extrapleural pleuropneumonectomy (25 patients) led to significant reductions in total lung capacity (4.8L to 3.5L) and vital capacity (2.8L to 1.8L).
  • Other pulmonary function parameters were also significantly diminished following extrapleural pleuropneumonectomy.

Conclusions:

  • Pleurectomy/decortication is associated with preserved pulmonary function.
  • Extrapleural pleuropneumonectomy results in significant pulmonary function decline, potentially leading to dyspnea and reduced quality of life.