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Minimally invasive pectus excavatum repair: migration of bar and ossification

Tiziano De Giacomo1, Daniele Diso, Federico Francioni

  • 1Department of Surgery and Transplantation P. Stefanini Thoracic Surgery Unit, University of Rome Sapienza, Policlinico Umberto I, Rome, Italy. tiziano.degiacomo@tin.it

Asian Cardiovascular & Thoracic Annals
|February 23, 2013
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Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...