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Related Concept Videos

Chronic Obstructive Pulmonary Disease II: Emphysema01:23

Chronic Obstructive Pulmonary Disease II: Emphysema

Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.
Pneumothorax-I01:26

Pneumothorax-I

A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Chronic Pharyngitis01:23

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations01:19

Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations

Chronic Obstructive Pulmonary Disease, or COPD, is a long-term condition marked by persistent and only partially reversible airflow limitation. It involves two overlapping conditions—chronic bronchitis and emphysema—which often co-appear but differ in dominant symptoms and underlying mechanisms.Chronic Bronchitis FeaturesChronic bronchitis presents with a persistent productive cough and thick, sometimes purulent mucus due to airway inflammation, enlarged mucus glands, and goblet cell...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.

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Related Experiment Video

Updated: May 14, 2026

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
15:43

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Published on: March 17, 2014

Chronic tension empyema.

Atsushi Sano1, Tomohiro Murakawa, Jun Nakajima

  • 1Department of Thoracic Surgery, The University of Tokyo Hospital,Tokyo, Japan. sanoa-tky@umin.ac.jp

Asian Cardiovascular & Thoracic Annals
|February 23, 2013
PubMed
Summary

Surgical removal of a chronic empyema capsule relieved lung compression in a patient with a 25-year history of tuberculosis empyema. This intervention improved the patient's overall lung function.

Area of Science:

  • Thoracic Surgery
  • Pulmonology
  • Infectious Disease Management

Background:

  • Chronic tuberculous empyema is a persistent infection of the pleural space, often leading to significant lung complications.
  • Long-standing empyema can cause pleural thickening and fibrosis, potentially leading to lung entrapment and compression.
  • Tension empyema, characterized by progressive enlargement of the empyema cavity, poses a risk of mediastinal shift and cardiorespiratory compromise.

Observation:

  • A 60-year-old male presented with a 25-year history of left tuberculous empyema.
  • The patient was diagnosed with chronic tension empyema due to significant enlargement of the empyema cavity.
  • Enlargement of the empyema cavity was causing compression of the heart and the left lung.

Findings:

Related Experiment Videos

Last Updated: May 14, 2026

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
15:43

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Published on: March 17, 2014

  • Surgical decortication (empyema capsule removal) was performed to alleviate compression.
  • The procedure successfully relieved the compression of the left lung.
  • Post-operative assessment indicated an improvement in the patient's lung function.
  • Implications:

    • Empyema capsule removal is an effective treatment for chronic tension empyema causing cardiorespiratory compression.
    • This surgical approach can lead to significant improvement in pulmonary function in patients with long-standing empyema.
    • Management of chronic tuberculous empyema requires consideration of surgical intervention to prevent long-term pulmonary sequelae.