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Viability Assay of Trichoderma stromaticum Conidia Inside Human Peripheral Blood Mononuclear-Derived Macrophages
Published on: October 20, 2023
Comparative transcriptomics reveals different strategies of Trichoderma mycoparasitism
Lea Atanasova1, Stephane Le Crom, Sabine Gruber
1Research Area Biotechnology and Microbiology, Institute of Chemical Engineering, Vienna University of Technology, Gumpendorferstrasse 1a, A-1060, Vienna, Austria.
BMC Genomics
|February 26, 2013
Summary
This study reveals distinct transcriptomic responses in Trichoderma fungi when interacting with Rhizoctonia solani. These findings illuminate diverse mycoparasitism mechanisms for developing novel biofungicides.
Area of Science:
- Mycology
- Fungal Genetics
- Plant Pathology
Background:
- Trichoderma fungi exhibit diverse lifestyles, including mycoparasitism for biological control.
- Mycoparasitism is crucial for plant protection against soil-borne fungal diseases.
- Understanding Trichoderma's interaction mechanisms is key for developing biofungicides.
Purpose of the Study:
- To compare the transcriptional responses of different Trichoderma species during confrontation with Rhizoctonia solani.
- To investigate the molecular mechanisms underlying Trichoderma's mycoparasitic interactions.
- To explore ecological strategies differentiating Trichoderma species.
Main Methods:
- Genome-wide transcriptomic analysis of three Trichoderma species (T. atroviride, T. virens, T. reesei).
- Comparative analysis of gene expression profiles during confrontation with the plant pathogenic fungus Rhizoctonia solani.
- Investigation of gene distribution and potential regulation via chromatin modification.
Main Results:
- Distinct transcriptomic profiles were observed in T. atroviride, T. virens, and T. reesei even before physical contact.
- T. atroviride upregulated genes for secondary metabolites and proteases.
- T. virens focused on gliotoxin biosynthesis, while T. reesei upregulated cellulases and solute transport genes.
Conclusions:
- Trichoderma mycotrophy has diversified into various ecological strategies, including parasitism, predation, and saprotrophy.
- This study provides initial insights into Trichoderma-fungi interactions for biofungicide development.
- Differential gene regulation and potential chromatin modification influence these interactions.
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