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Updated: May 13, 2026
Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Comparison of central corneal thickness measured with anterior segment optical coherence tomography versus ultrasonic
C Lázaro1, E M Hernández, D Martínez
1Servicio de Oftalmología, Hospital Provincial de la Misericordia, Toledo, Spain. carloslazarogarcia@gmail.com
Purpose:
To compare central corneal thickness measured with anterior segment optical coherence tomography (AS-OCT) and ultrasonic pachymetry (UP).
Method:
A prospective, observational and cross-sectional study was performed. The central corneal thickness was measured in 112 eyes of 112 consecutive patients with AS-OCT and UP. All examinations were performed by the same examiner. The measurements obtained between the 2 instruments were compared to assess the level of agreement.
Results:
The average corneal thickness value obtained by AS-OCT was 531.47 ± 26.23 μm, while that measured by UP was 532.51 ± 26.04 μm. The intraclass correlation coefficient was 0.957 (P <.001). The Student's t-test did not show a statistically significant difference (1.04 ± 7.70 μm, P =.158). Finally, the Bland-Altman analysis showed a high level of agreement between 2 methods of measurement.
Conclusions:
In the context of normal corneas, there was good agreement between the measurement of central corneal thickness with AS-OCT and UP, although there was a slight overestimation of the measurement using UP (1.04 μm).
