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A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
16:40

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation

Published on: February 28, 2012

Long-term complications of implantable defibrillator therapy in Brugada syndrome

Shinsuke Miyazaki1, Takashi Uchiyama, Yuki Komatsu

  • 1Cardiovascular Center, Tsuchiura Kyodo Hospital, Ibaraki, Japan. mshinsuke@k3.dion.ne.jp

The American Journal of Cardiology
|February 26, 2013
PubMed

Insights

Implantable cardioverter-defibrillator (ICD) complications are common in Brugada syndrome (BrS) patients, increasing over time. Careful selection and education are crucial for young, asymptomatic BrS patients considering ICD therapy.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Implantable cardioverter-defibrillator (ICD) therapy is beneficial for Brugada syndrome (BrS) patients at risk of sudden cardiac arrest.
  • Long-term complications associated with ICDs can affect younger patient populations.

Purpose of the Study:

  • To determine the incidence of device complications in BrS patients during long-term follow-up.
  • To assess the clinical outcomes and prevalence of device-related issues in BrS patients with ICDs.

Main Methods:

  • Retrospective analysis of 41 consecutive BrS patients who underwent ICD implantation.
  • Median follow-up of 76 months to record adverse events, including device complications and shocks.

Main Results:

  • 37% of patients experienced adverse events, with 20% having device-related complications and 24% receiving inappropriate shocks.
  • 12% of patients received appropriate shocks for ventricular fibrillation.
  • Long-term complication-free rates (excluding inappropriate shocks) decreased over time, with 73.3% free at 7 years.

Conclusions:

  • Adverse effects of ICD implantation are frequent in BrS patients and increase with follow-up duration.
  • Asymptomatic young BrS patients require careful selection for ICD therapy.
  • Patients should be thoroughly educated about the potential long-term outcomes and risks of ICDs.

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