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Related Concept Videos

Proofreading01:43

Proofreading

Overview
Proofreading01:31

Proofreading

Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase Enzyme
Proofreading01:43

Proofreading

Overview
Genome Copying Errors02:46

Genome Copying Errors

DNA replication is a well-evolved process that copies millions of base pairs with high fidelity during each cell division. Occasionally a wrong base or a long stretch of wrong bases may get added to the daughter strands. If the errors are left unchecked, cells might accumulate several mutations that might endanger their  survival. Therefore, the copying errors are checked and repaired at three levels.
Threats to Biodiversity01:50

Threats to Biodiversity

There have been five major extinction events throughout geological history, resulting in the elimination of biodiversity, followed by a rebound of species that adapted to the new conditions. In the current geological epoch, the Holocene, there is a sixth extinction event in progress. This mass extinction has been attributed to human activities and is thus provisionally called the Anthropocene. In 2019 the human population reached 7.7 billion people and is projected to comprise 10 billion by...
Replication in Prokaryotes02:35

Replication in Prokaryotes

Overview

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Related Experiment Video

Updated: May 13, 2026

Transformation of Plasmid DNA into E. coli Using the Heat Shock Method
07:46

Transformation of Plasmid DNA into E. coli Using the Heat Shock Method

Published on: August 1, 2007

[Plagiarism. A challenge for editors]

Alberto Ruano-Ravina, Carlos Alvarez-Dardet, Ana M García

    Medicina Clinica
    |February 26, 2013
    PubMed
    Summary

    No abstract available in PubMed .

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