Related Experiment Video
Updated: May 13, 2026

Optogenetic Activation of Afferent Pathways in Brain Slices and Modulation of Responses by Volatile Anesthetics
Published on: July 23, 2020
Neuroanesthesiology update
Jeffrey J Pasternak1, William L Lanier
1Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. pasternak.jeffrey@mayo.edu
Abstract:
We provide a review of both clinical and basic science literature from 2012 relevant to care of the patient with neurological disease. Our review addresses the following major areas: general neurosurgical procedures, stroke, traumatic brain injury, spine surgery, anesthetic neurotoxicity, neuroprotective strategies, electrophysiological monitoring, history, and graduate medical education. We have focused on research describing new and innovative concepts and recurring themes. This review is intended to be of interest to those working in the clinical arena and also to neuroscientists.
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