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[The neuraminic acid/protein quotient in amniotic fluid: indicator for fetal maturity]
1Institut für Pathologische Biochemie, Medizinischen Akademie Magdeburg.
Zeitschrift Fur Medizinische Laboratoriumsdiagnostik
|January 1, 1990
Abstract:
The concentration of neuraminic acid and proteins was determined in amniotic fluid of 207 pregnancies during the amniocentesis, performed in the 16.-21. week of gestation, 17 prematurities and 101 deliveries in time. The neuraminic acid/protein quotient increases significantly at term. Than, its reference range is 51.3-154.8 mumol/g (2.5-97.5 percentile). The neuraminic acid/protein quotient can be an useful prenatal indicator of the fetal maturity because of its high diagnostic specificity (97%) and sensitivity (88%).