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Updated: May 13, 2026

Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
Published on: July 30, 2017
Development of intramolecular vicinal diamination of alkenes: from palladium to bromine catalysis
Kilian Muñiz1, Claudio Martínez
1Institute of Chemical Research of Catalonia (ICIQ), Av. Països Catalans, 16, E-43007 Tarragona, Spain. kmuniz@iciq.es
Abstract:
Palladium catalysis has been instrumental in the development of the intramolecular diamination of alkenes. Reagent combinations of a palladium catalyst and iodosobenzene diacetate or copper(II) salts, respectively, represent the broad applicability and mechanistic variation. Recent work has established alternative copper and bromine catalysts. The occupation with this reaction has also contributed to the development of high oxidation state metal catalysis in alkene difunctionalization and significantly broadened the spectrum of Pd-catalyzed C-N bond-forming reactions in general.
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